Plants containing pyrrolizidine alkaloids: toxicity and problems
نویسندگان
چکیده
منابع مشابه
Plants containing pyrrolizidine alkaloids: toxicity and problems.
Pyrrolizidine alkaloids (PA) are toxic for human and livestock. They undergo a metabolic toxication process in the liver which is the first target organ for PA poisoning. Worldwide many episodes of human PA intoxications are well reported. In many cases the reason for these intoxications has been PA contamination in food. The main tools for analysing food and fodder on PA content are based on G...
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Investigation of the pyrrolizidine alkaloids of Heliotropium arbainense resulted in the isolation and identification of heliotrine, europine and 7-angelylheliotrine. From H. ovalifolium three alkaloids were isolated: supinine, 7-angelylheliotridine and an alkaloid which was shown to be of the heliotridine monoester type with a dehydrated viridifloric acid.
متن کاملQualitative and Quantitative Study of Pyrrolizidine Alkaloids in Medicinal Plants Sold in Herb Shops
Background and purpose: Pyrrolizidine alkaloids (PAs) are a group of chemical compounds that are seen as secondary metabolites in different plant families. These compounds can cause liver, kidney, and lung damages and their presence in various herbal products increases the risk of injury. This study aimed at performing qualitative and quantitative evaluation of pyrrolizidine alkaloids in medic...
متن کاملToxicity Profile of Pyrrolizidine Alkaloid-Containing Medicinal Plants: Emphasis on Senecio Species
Pyrrolizidine alkaloids (PAs) are found in various plant genera worldwide. Poisoning by PA-containing plants is usually accidental, by the ingestion of grain inadvertently contaminated with seeds of pyrrolizidine-containing weeds, or the consumption of herbal or bush tea, or when taken as herbal infusions for medicinal purposes. In this paper the toxicity of PA-containing plants, with emphasis ...
متن کاملPyrrolizidine alkaloids in human diet.
Pyrrolizidine alkaloids are the leading plant toxins associated with disease in humans and animals. Upon ingestion, metabolic activation in liver converts the parent compounds into highly reactive electrophiles capable of reacting with cellular macromolecules forming adducts which may initiate acute or chronic toxicity. The pyrrolizidine alkaloids present a serious health risk to human populati...
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ژورنال
عنوان ژورنال: Food Additives & Contaminants: Part A
سال: 2011
ISSN: 1944-0049,1944-0057
DOI: 10.1080/19440049.2010.541288